Peptide Stacks
Popular peptide combinations with evidence summaries, synergy mechanisms, and research citations.
Many peptides are used in combination to target complementary pathways — from the BPC-157 + TB-500 recovery stack to growth hormone secretagogue pairings and GLP-1 formulations with nutrient support. Each stack page explains why the peptides are combined, the proposed synergy mechanism, what the evidence actually shows, and important considerations for clinical use.
Weight Loss
GLP-1 agonist combinations and amylin/incretin co-administrations targeting body weight and metabolic health.
Semaglutide + B12 (Compounded Semaglutide)
The most commonly prescribed compounded semaglutide formulation for weight loss. Pairs GLP-1 therapy with vitamin B12 to address nutrient absorption concerns and support energy during caloric restriction. Often includes glycine.
CagriSema / CagriTriz / CagriReta (Cagrilintide + GLP-1 Agonist)
A family of weekly injectable obesity stacks that pair the long-acting amylin analog cagrilintide with a GLP-1 receptor agonist — semaglutide (CagriSema), tirzepatide (CagriTriz), or retatrutide (CagriReta). Only CagriSema has completed pivotal clinical trials; the other two are conceptual compounded or investigational combinations.
Healing & Recovery
Tissue repair, wound healing, and post-injury stacks built around BPC-157, TB-500, GHK-Cu, and KPV.
Wolverine Peptide Stack (BPC-157 + TB-500)
The Wolverine Stack is the most popular peptide recovery combination — BPC-157 for localized tissue repair paired with TB-500 for systemic healing, cell migration, and anti-inflammatory support.
GLOW Peptide Stack (BPC-157 + TB-500 + GHK-Cu)
GLOW is a popular pre-mixed compounded peptide blend combining BPC-157 tissue repair, TB-500 cell migration, and GHK-Cu collagen remodeling in a single 70 mg vial. Also covers the two-peptide BPC-157 + GHK-Cu pairing for practitioners sourcing vials separately.
KLOW Peptide Stack (BPC-157 + TB-500 + GHK-Cu + KPV)
KLOW is a pre-mixed four-peptide compounded blend combining BPC-157 and TB-500 systemic repair, GHK-Cu collagen remodeling, and KPV anti-inflammatory coverage in a single 80 mg vial. It extends the popular GLOW formulation with an explicit anti-inflammatory layer.
Growth Hormone
GHRH-analog plus ghrelin-mimetic pairings designed to amplify the body's natural pulsatile GH release.
CJC-1295 + Ipamorelin (The GH Secretagogue Stack)
The classic growth hormone secretagogue stack — often called the GH stack or sleep stack. Combines GHRH signaling (CJC-1295) with selective ghrelin receptor activation (ipamorelin) to amplify the body's natural nighttime growth hormone pulse.
Tesamorelin + Ipamorelin (FDA-Backed GHRH Analog + Selective Ghrelin-Mimetic)
A growth hormone secretagogue stack that pairs the only FDA-approved GHRH analog (tesamorelin) with the cleanest ghrelin-receptor trigger (ipamorelin). Delivers the same GHRH + ghrelin dual-pathway synergy as CJC-1295 + ipamorelin, with tesamorelin's Phase III evidence base standing in for the compounded GHRH leg.
Sermorelin + Glycine (The Sleep & GH Stack)
Pairs sermorelin's growth hormone-releasing activity with glycine's sleep-enhancing and metabolic benefits for optimized nighttime GH release and recovery.
Longevity & Mitochondrial
Concept stacks targeting NAD+ pool, sirtuins, AMPK, and mitochondrial-derived peptide signaling.
Cognitive & Mood
Neuropeptide combinations for focus, anxiety, and stress resilience.
Sexual Wellness
Stacks pairing central arousal signaling with bonding and intimacy support.
Immune & Inflammation
Combinations targeting systemic immune modulation alongside local anti-inflammatory action.